The San Francisco 49ers are preparing for their Week 18 contest against the Arizona Cardinals on Sunday at Levi's Stadium in Santa Clara, California.
Several 49ers stars didn't suit up for the first practice of the week. Many of the names, like quarterback Jimmy Garoppolo and guard Aaron Banks, aren't surprising.
Christian McCaffrey's name popped up on Monday's injury report from head coach Kyle Shanahan. The running back is dealing with what the coach called a "mild" ankle sprain and did not practice on Wednesday. The injury occurred on Sunday against the Las Vegas Raiders. Although, Shanahan wasn't sure exactly when it happened during the game.
Linebacker Dre Greenlaw sustained a back injury against the Raiders. He did not practice. The 49ers rested defensive end Nick Bosa and tackle Trent Williams.
Guard Aaron Banks has already been ruled out against the Cardinals due to knee and ankle sprains sustained against the Raiders.
Below are Wednesday's practice participation reports for both the 49ers and Cardinals, which were provided by the 49ers Communications staff.
San Francisco 49ers Wednesday Practice
Did Not Participate In Practice
OL Aaron Banks (ankle, knee), DL Nick Bosa (not injury related - resting player), QB Jimmy Garoppolo (foot), DL Kevin Givens (knee), LB Dre Greenlaw (back), DT Javon Kinlaw (knee), RB Christian McCaffrey (ankle, knee), T Trent Williams (not injury related - resting player)
Limited Participation in Practice
DL Arik Armstead (foot, ankle), CB Ambry Thomas (ankle)
Full Participation in Practice
QB Brock Purdy (oblique, rib), WR Deebo Samuel (ankle, knee)
Arizona Cardinals Wednesday Practice
Did Not Participate In Practice
DE Zach Allen (hand), WR Robby Anderson (back), S Chris Banjo (concussion), T Kelvin Beachum (knee, ankle), LB Zaven Collins (calf), RB James Conner (knee, shin), CB Antonio Hamilton (hip), WR DeAndre Hopkins (knee), DE Jonathan Ledbetter (knee), QB Colt McCoy (concussion)
DT Leki Fotu (shoulder), CB Josh Jackson (hamstring), C Billy Price (knee), LB Isaiah Simmons (ankle), LB Tanner Vallejo (knee, wrist), CB Marco Wilson (neck)
Full Participation in Practice
WR Marquise Brown (wrist)