The 49ers (4-11) could jump up to the top overall selection should the Arizona Cardinals (3-12) manage an upset win over the Seattle Seahawks — a game which takes place at the same time as 49ers vs. Rams. Seattle is a 14-point favorite in that matchup.
The 49ers are a 10.5-point underdog in their game against the Rams at the Los Angeles Memorial Coliseum.
The New York Jets (4-12) lost to the New England Patriots but currently still own a stronger strength of schedule compared to San Francisco. The strength of schedule is used as the tiebreaker between teams with matching records.
The only other four-win team is the Oakland Raiders, who will face the Kansas City Chiefs as the 49ers battle the Rams.
The 49ers head into their game with a .500 strength of schedule. The Jets sit at .510 and the Raiders at .544. The Cardinals own a .527 strength of schedule. Those numbers will change slightly based on the results from the afternoon games.
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