The 49ers did not practice on Monday and held walkthroughs on Tuesday and Wednesday.
There was some concern that running backs Matt Breida and Raheem Mostert might not be available for Thursday's game. Kyle Shanahan said on KNBR Wednesday morning that there is a good chance that both will play.
"I don't think it would be an issue if we were playing Sunday," Shanahan added. "It's just a little bit of an issue because of how quick this game is coming. So when we travel there tonight, really, how they wake up in the morning will be the biggest (indicator). Sometimes there's always a little effect when you travel, just the swelling and things like that.
"If they aren't good enough to go, obviously they won't, but just knowing Breida, knowing Raheem, I have a feeling they'll be alright."
The head coach didn't sound as optimistic about left tackle Joe Staley's chances of returning to face the Cardinals. Staley suffered a fractured fibula during Week 2.
"Staley, I'd say, has the worst [chance of playing]," Shanahan added.
Below are the official injury reports for the 49ers and Cardinals, which were provided by the 49ers Communications staff. Also included are this week's practice participation reports.
San Francisco 49ers
| Player | Injury | Mon | Tue | Wed | Game Status |
| Matt Breida | ankle | LP | LP | LP | Questionable |
| Dee Ford | quadricep | LP | LP | LP | |
| Kyle Juszczyk | knee | DNP | DNP | DNP | Out |
| Mike McGlinchey | knee | DNP | DNP | DNP | Out |
| Raheem Mostert | knee | LP | LP | LP | Questionable |
| Justin Skule | knee, foot | LP | LP | LP | |
| Joe Staley | fibula | LP | LP | LP | Doubtful |
| Levine Toilolo | groin | LP | LP | LP | Questionable |
| Ahkello Witherspoon | foot | DNP | DNP | DNP | Out |
Arizona Cardinals
| Player | Injury | Mon | Tue | Wed | Game Status |
| Zach Allen | neck | DNP | DNP | DNP | Out |
| Darrell Daniels | ankle | DNP | DNP | DNP | |
| Chase Edmonds | hamstring | DNP | DNP | DNP | Out |
| Dennis Gardeck | ankle | DNP | DNP | DNP | |
| David Johnson | ankle | DNP | DNP | DNP | Questionable |
| Cassius Marsh Sr. | concussion | DNP | DNP | DNP | |
| Justin Murray | knee | DNP | DNP | DNP | Questionable |
| Haason Reddick | knee | DNP | DNP | DNP | |
| Trent Sherfield | knee | DNP | DNP | DNP | |
| Charles Clay | back | LP | LP | LP |
DNP - Did not participate in practice
LP - Limited participation in practice
FP - Full participation
NIR - Not injury related
More San Francisco 49ers News
-
Mock draft has 49ers selecting tackle coming off injury
After enduring an injury-plagued 2024 campaign, San Francisco 49ers fans likely aren't eager to see their team add any players with injury concerns via the 2025 NFL Draft. However, NFL Network's Rhett Lewis has the Bay Area team doing just that in his first mock draft of the... -
Bleacher Report links C.J. Mosley to 49ers as free-agent fit
Most expect the San Francisco 49ers to address the linebacker position in the 2025 NFL Draft following the departure of Dre Greenlaw in free agency. After the Denver Broncos extended an offer to Greenlaw, head coach Kyle Shanahan and general manager John Lynch flew to Texas in... -
49ers conduct pre-draft meeting with Pitt WR Konata Mumpfield
The San Francisco 49ers are entering the final stretch of preparations for the 2025 NFL Draft and are continuing to wrap up their pre-draft evaluations. As part of the process, the team is meeting with various draft prospects, with many of those interviews taking place... -
49ers surpass Ravens for rushing records after NFL incorporates AAFC stats
The 2019 Baltimore Ravens rushed for an impressive 3,296 yards during the regular season, setting what was then the NFL record for most rushing yards in a single season—until now. This week, the NFL announced it would begin incorporating statistics from the All-America...