Kittle was able to walk off the field under his own power. He was examined in the medical tent before exiting and putting his helmet back on. Kittle could be seen jogging along the sideline, which is a good indication that the injury isn't too serious.
The 49ers currently trail the Cardinals 7-0 at State Farm Stadium.
Ross Dwelley is the 49ers' only remaining healthy tight end. Levine Toilolo has been dealing with a groin injury this week and was limited in the team's two walkthroughs. He entered the game listed as "questionable" to play.
Defensive lineman Arik Armstead also left the game and was seen on the sideline being examined by the medical staff.
Update: Several reporters are noting that it looks like Armstead might be battling an illness.
Related News
More San Francisco 49ers News
-
George Kittle reveals Kyle Shanahan's message to 49ers after frustrating loss to Packers
San Francisco 49ers players were visibly dejected while speaking to reporters after Sunday's demoralizing 38-10 defeat to the Green Bay Packers. Wide receiver Deebo Samuel declined to talk with the media after a frustrating one-catch performance. "It's probably one of the... -
49ers Notebook: Reflecting on playing in snowy weather; Kyle Juszczyk laments key fumble; Why didn't George Kittle get more targets vs. Bills?
The weather outside was frightful at Highmark Stadium in Orchard Park, New York on Sunday night, but the way the San Francisco 49ers played against the Buffalo Bills inside the stadium was even worse. The 49ers gave up 220 yards on the ground, turned the ball over three times,... -
49ers Notebook: George Kittle's sunny optimism; Fred Warner on 'embarrassing' loss; Shanahan explains '12 men' penalties
After their 38-10 loss to the Packers at Lambeau Field in Green Bay on Sunday, the San Francisco 49ers felt like a team whose season was on the brink. They remained only one game back of the Arizona Cardinals and Seattle Seahawks in the NFC West standings after the loss, but a... -
Brandon Allen gets support from Shanahan, Kittle after first 49ers start
Brandon Allen didn't do enough to be counted among the rare bright spots in the 49ers' dreadful 38-10 road loss to the Green Bay Packers on Sunday, but head coach Kyle Shanahan and tight end George Kittle found enough positives in the veteran quarterback's performance to give...