Ian Rapoport of NFL Network reported on Friday morning that Pettis suffered a sprained knee and that it is not considered to be a long-term injury.
Head coach Kyle Shanahan confirmed Rapoport's report on Friday, telling reporters that the second-year receiver will not play on Sunday against the Baltimore Ravens and is week-to-week with a sprained knee.
"He sprained his knee Wednesday," Shanahan said. "Just a non-contact drill. Him and a couple of players got tangled up, and just sprained his knee. He'll be week-to-week with that."
Shanahan wasn't able to clarify on the severity of the sprain.
The 49ers made Pettis a second-round draft pick out of Washington in 2018. He has just 11 receptions for 109 yards with two touchdowns through 11 games this season, but has been held without a catch during San Francisco's last three games.
More San Francisco 49ers News
-
49ers vs. Rams final injury report: Williams among 3 ruled out for TNF; Guerendo, Bosa questionable
The San Francisco 49ers are preparing for their Week 15 contest against the Los Angeles Rams on Thursday at Levi's Stadium in Santa Clara, California. Both teams have released their official injury reports, which are provided below. San Francisco 49ers Out G Ben Bartch... -
Brock Purdy update: Kyle Shanahan says 49ers QB has been 'great all week'
49ers quarterback Brock Purdy struggled during last Sunday's game against the Buffalo Bills. Difficult weather conditions and his recent recovery from a shoulder injury likely contributed to his performance. This week, Purdy has been a full participant in practice and is... -
Kyle Shanahan, Brock Purdy share final updates ahead of 49ers-Bears Week 14 matchup
San Francisco 49ers head coach Kyle Shanahan and quarterback Brock Purdy spoke with reporters after Friday's practice as the team prepares for its Week 14 matchup against the Chicago Bears. Here's everything they said. Transcripts provided by the San Francisco 49ers... -
Kyle Shanahan on benefits and challenges of short week ahead of 49ers-Rams showdown
After playing on Sunday afternoon, the San Francisco 49ers face a quick turnaround as they prepare to host the Los Angeles Rams on Thursday night. A compressed week like this presents unique challenges, especially for a team dealing with injuries—a recurring issue for the...