Maybe that still happens. But the 49ers will need to get back some of the players from their growing injury list.
The defensive line, which is vital to the defense's success, has already taken a significant hit with the losses of two former first-round picks in Nick Bosa and Solomon Thomas. Both saw their seasons end during Week 2 after suffering torn ACLs.
Here is an updated list of the 49ers' current injury situation.
| Player | Pos | Injury | Status |
| Tavon Austin | WR | Knee | IR, out for season |
| Ronald Blair | DE | Torn ACL (2019) | PUP through Week 6 |
| Nick Bosa | DE | Torn ACL | Out for season |
| Tevin Coleman | RB | Knee sprain | Out multiple weeks |
| Dee Ford | DE | Back | Unknown |
| Jimmy Garoppolo | QB | High-ankle sprain | Week-to-week |
| Dre Greenlaw | LB | Thigh contusion | Unknown |
| Tim Harris* | CB | Calf | IR through Week 4 |
| Jalen Hurd | WR | Torn ACL | IR, out for season |
| Richie James Jr. | WR | Hamstring strain | IR through Week 4 |
| D.J. Jones | DT | Ankle | Unknown |
| George Kittle | TE | MCL sprain, bone bruise | Week-to-week |
| Raheem Mostert | RB | MCL sprain | Week-to-week |
| Weston Richburg | C | Torn patellar (2019) | PUP through Week 6 |
| Deebo Samuel | WR | Jones fracture | IR through Week 3 |
| Richard Sherman | CB | Calf strain | IR through Week 4 |
| Jullian Taylor | DL | Torn ACL (2019) | PUP through Week 6 |
| Solomon Thomas | DL | Torn ACL | Out for season |
| Chris Thompson** | WR | Unknown | IR, out for season |
| Jason Verrett | CB | Hamstring strain | day-to-day |
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