Ian Rapoport of NFL Network reports that Williams suffered a "somewhat rare ACL sprain," but that three weeks timeline seems to be an appropriate estimate for the defender's recovery.
Williams, 29, left Sunday night's game in the fourth quarter after a collision with an Eagles player. He limped off the field under his own power, left for the team's locker room, and was listed as "questionable" to return.
Jamar Taylor replaced Williams.
Williams has recorded 12 tackles and two passes defensed in four games and two starts this season.
More San Francisco 49ers News
-
49ers vs. Packers injury report: Purdy briefly throws before exiting practice; Still no Williams, Bosa
The San Francisco 49ers are preparing for their Week 12 contest against the Green Bay Packers on Sunday at Lambeau Field in Green Bay, Wisconsin. Brock Purdy, who refrained from throwing during Wednesday's practice due to a shoulder injury, resumed light throwing to team staff... -
Shanahan provides latest intel on Purdy's status for 49ers-Packers; Williams, Bosa updates
San Francisco 49ers quarterback Brock Purdy did not address reporters on Thursday, breaking his usual routine of speaking after the team's second practice of the week. Typically, the quarterback expected to start is made available to the media, making Purdy's absence noteworthy... -
49ers-Packers injury news: John Lynch provides Trent Williams and Nick Bosa updates
While the status of quarterback Brock Purdy has dominated headlines, injuries to tackle Trent Williams and defensive end Nick Bosa remain crucial storylines as the San Francisco 49ers prepare for their Week 12 matchup against the Green Bay Packers at Lambeau Field. On Friday... -
49ers vs. Packers injury report: Purdy, Bosa ruled out; Williams questionable
The San Francisco 49ers are preparing for their Week 12 contest against the Green Bay Packers on Sunday at Lambeau Field in Green Bay, Wisconsin. Both teams have released their official injury reports, which are provided below. San Francisco 49ers Out LB Tatum Bethune (knee),...