- WR River Cracraft and CB Saivion Smith promoted from the practice squad to the active roster
- RB Brian Hill and S Jarrod Wilson activated from the practice squad
- RB Trenton Cannon and CB Emmanuel Moseley placed on injured reserve
Cannon and Moseley sustained their injuries during Week 13's loss to the Seattle Seahawks. Cannon suffered a concussion on the opening kickoff return, while Moseley is dealing with a high-ankle sprain.
The 49ers also announced that cornerback Dontae Johnson has been downgraded from "questionable" to "out." That means one of the two rookie cornerbacks—Deommodore Lenoir or Ambry Thomas—will likely start opposite Josh Norman.
San Francisco enters Week 14 with a 6-6 record, while Cincinnati is 7-5. Kickoff between the two teams is scheduled for 1:25 p.m. PT from Paul Brown Stadium in Cincinnati. The 49ers are currently a 1.5-point favorite.
The two teams will announce their inactive players 90 minutes ahead of kickoff.
The NFL fined 49ers defensive end Arden Key $15,450 for roughing the passer on his hit of Seattle Seahawks quarterback Russell Wilson in Week 13, per The Athletic.
Seahawks defensive end Darrell Taylor was not fined for his hit to 49ers running back Elijah Mitchell's head, which resulted in a concussion. Mitchell remains in the concussion protocol, and San Francisco ruled him out for this weekend's game against the Bengals.
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