It looks like rookie quarterback Trey Lance will get the start this weekend with Jimmy Garoppolo dealing with a thumb injury. Garoppolo did not practice this week and is listed as "questionable."
Head coach Kyle Shanahan stated that the 49ers are still hoping that Garoppolo can play, which is why he hasn't been ruled out.
"No, I'm not ready to announce [Lance as the starter]," Shanahan said on Friday. "Jimmy's not out, so I'm holding out hope. [As for] next week, he's got a chance this week, so he'll have a better chance next week."
This week, Shanahan said that he expects the 49ers to activate running back Trey Sermon (ankle) off injured reserve ahead of Sunday's game. That move will likely come on Saturday.
San Francisco will be without a pair of linebackers—Dre Greenlaw and Azeez Al-Shaair. Both are ruled out.
Below are the official injury reports for the 49ers and Texans, which were provided by the 49ers Communications staff. Also included are Friday's practice participation reports.
San Francisco 49ers
Out
LB Azeez Al-Shaair (knee), LB Dre Greenlaw (groin), DL Maurice Hurst (calf)
Doubtful
QB Jimmy Garoppolo (right thumb), S Talanoa Hufanga (knee)
Questionable
RB Elijah Mitchell (knee)
Houston Texans
Out
QB Deshaun Watson (not injury related - personal matter)
Questionable
WR Chris Conley (knee), S A.J. Moore (illness), CB Jimmy Moreland (illness)
San Francisco 49ers Friday Practice
Did Not Participate In Practice
LB Azeez Al-Shaair (knee), QB Jimmy Garoppolo (right thumb), LB Dre Greenlaw (groin), S Talanoa Hufanga (knee), DL Maurice Hurst (calf)
Limited Participation in Practice
RB Elijah Mitchell (knee)
Full Participation in Practice
DL D.J. Jones (ankle), C Alex Mack (not injury related - resting player), T Trent Williams (not injury related - resting player)
Houston Texans Friday Practice
Did Not Participate In Practice
QB Deshaun Watson (not injury related - personal matter)
Limited Participation in Practice
WR Chris Conley (knee), S A.J. Moore (illness), CB Jimmy Moreland (illness)
Full Participation in Practice
C Justin Britt (knee), DE Jonathan Greenard (foot), LB Kamu Grugier-Hill (knee), DE Jordan Jenkins (knee), DE DeMarcus Walker (hamstring)
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