Inactives:
- LB Marcell Harris (Achilles)
- DL Maurice Hurst
- CB Deommodore Lenoir
- OL Jaylon Moore
- RB Trey Sermon
- CB Ambry Thomas (knee)
- DB Jarrod Wilson
Thomas, a rookie, was one of three 49ers players listed as "questionable" for the game. The other two, defensive linemen Nick Bosa (concussion) and Jordan Willis (ankle), are active.
"I'm hoping he'll go," head coach Kyle Shanahan said of Thomas on Thursday. "That's why we've got him as 'questionable.' I think he'll be alright, but that will come down to seeing how he is on game day."
Thomas, a starter in last weekend's playoff win against the Dallas Cowboys, emerged from that game with a bone bruise in his knee. His absence means either Josh Norman or Dontae Johnson gets the start opposite Emmanuel Moseley.
The 49ers' other rookie cornerback, Lenoir, is also inactive. Rookie running back Trey Sermon has yet to be active for a game since coming off injured reserve on January 11, ahead of the playoff matchup against the Cowboys.
Saturday's game will be the third straight in which Harris has been inactive.
Bosa cleared the concussion protocol on Friday and will play. The 49ers also activated defensive back Darqueze Dennard and linebacker Mark Nzeocha from the practice squad.
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