The NFL revealed its complete 272-game 2022 regular-season schedule on Thursday at 5:00 p.m. PT. NFL Kickoff Weekend will begin on Thursday, September 8, culminating with Super Bowl LVII on February 12, 2023, at State Farm Stadium in Glendale, Arizona.

The San Francisco 49ers open their season on the road against the Chicago Bears. Their first home game comes during Week 2 against the Seattle Seahawks.

The Niners' bye is during Week 9. They are currently scheduled to participate in five prime-time matchups this year.

San Francisco's opponents combined for a 154-135 record last season. The .533 winning percentage by opponents makes the 49ers' schedule tied with the Kansas City Chiefs for the fifth toughest in the NFL, based on last year's results, and the third-toughest among NFC West teams with only the Seattle Seahawks owning an easier strength of schedule (SOS). That's a significant jump from last season's SOS, which tied for 19th.


Below is the complete 2022 49ers schedule, which you can also find on our official schedule page.

Preseason


Date Ranges Opponent Local Time Pacific Time Network
August 11-15 Green Bay TBD TBD
August 18-22 at Minnesota TBD TBD
August 25 at Houston 7:00 p.m. 5:00 p.m. Prime Video

Regular Season


Date Opponent Local Time Pacific Time Network
Sunday, September 11 at Chicago 12:00 p.m. 10:00 a.m. FOX
Sunday, September 18 Seattle 1:05 p.m. FOX
Sunday, September 25 at Denver 6:20 p.m. 5:20 p.m. NBC
Monday, October 3 Los Angeles Rams 5:15 p.m. ESPN
*Sunday, October 9 at Carolina 4:05 p.m. 1:05 p.m. CBS
*Sunday, October 16 at Atlanta 1:00 p.m. 10:00 a.m. FOX
*Sunday, October 23 Kansas City 1:25 p.m. FOX
*Sunday, October 30 at Los Angeles Rams 1:25 p.m. FOX
Sunday, November 6 BYE
*Sunday, November 13 Los Angeles Chargers 5:20 p.m. NBC
Monday, November 21 at Arizona (Mexico City) 7:15 p.m. 5:15 p.m. ESPN
*Sunday, November 27 New Orleans 1:25 p.m. FOX
*Sunday, December 4 Miami 1:05 p.m. FOX
*Sunday, December 11 Tampa Bay 1:25 p.m. FOX
Thursday, December 15 at Seattle 5:15 p.m. Prime Video
Saturday, December 24 Washington 1:05 p.m. CBS
*Sunday, January 1 at Las Vegas 1:05 p.m. FOX
*^Sat or Sun, Jan 7-8 Arizona TBD TBD

This season, "flexible scheduling" for Sunday night may be used twice between Weeks 5-10, and during Weeks 11-15 and Week 17. In weeks of the season eligible for "flexible scheduling," the games listed for the Sunday night window are tentative and subject to change. Only Sunday afternoon games are eligible to be moved to Sunday night, in which case the tentatively scheduled Sunday night game would be moved to a Sunday afternoon.

Flexible scheduling will not be applied to games airing on Thursday or Monday nights.

In Week 15, three of five designated matchups will be played on Saturday with the remainder to be played on Sunday. Specific dates and start times for the designated Week 15 matchups will be determined and announced at a later date during the season.

^In Week 18, two games will be played on Saturday (4:30 PM ET and 8:15 PM ET) with the remainder to be played on Sunday afternoon (1:00 PM ET and 4:25 PM ET) and one matchup to be played on Sunday night (8:20 PM ET). Specific dates, start times, and networks for Week 18 matchups will be determined and announced following the conclusion of Week 17.



Notes


Provided by the 49ers Communications staff.

A Closer Look at the 2022 Schedule…


Week 1 – Sunday, September 11 at Chicago – 10:00 a.m. PT on FOX


Week 2 – Sunday, September 18 vs. Seattle – 1:05 p.m. PT on FOX


Week 3 – Sunday, September 25 at Denver – 5:20 p.m. PT on NBC



Week 4 – Monday, October 3 vs. Los Angeles Rams – 5:15 p.m. PT on ESPN


Week 5 – Sunday, October 9 at Carolina – 1:05 p.m. PT on CBS


Week 6 – Sunday, October 16 at Atlanta – 10:00 a.m. PT on FOX


Week 7 – Sunday, October 23 vs. Kansas City – 1:25 p.m. PT on FOX


Week 8 – Sunday, October 30 at Los Angeles Rams – 1:25 p.m. PT on FOX



Week 9 – Sunday, November 6 – BYE


Week 10 – Sunday, November 13 vs. Los Angeles Chargers – 5:20 p.m. PT on NBC


Week 11 – Monday, November 21 at Arizona (Mexico City) – 5:15 p.m. PT on ESPN


Week 12 – Sunday, November 27 vs. New Orleans – 1:25 p.m. PT on FOX


Week 13 – Sunday, December 4 vs. Miami – 1:05 p.m. PT on FOX



Week 14 – Sunday, December 11 vs. Tampa Bay – 1:25 p.m. PT on FOX


Week 15 – Thursday, December 15 at Seattle – 5:15 p.m. PT on Amazon Prime Video


Week 16 – Saturday, December 24 vs. Washington – 1:05 p.m. PT on CBS


Week 17 – Sunday, January 1 at Las Vegas – 1:05 p.m. PT on FOX


Week 18 – Saturday or Sunday, January 7-8 vs. Arizona




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