Inactives:
- OL Aaron Banks (ankle, knee)
- TE Ross Dwelley
- QB Jimmy Garoppolo (foot)
- DL Kevin Givens (knee)
- LB Dre Greenlaw (back)
- DL Drake Jackson
- CB Ambry Thomas (ankle)
On Friday, San Francisco ruled out five players due to injuries. They are Banks, Garoppolo, Givens, Greenlaw, and Thomas. Defensive linemen Arik Armstead (illness, foot, ankle) and Javon Kinlaw (illness, knee) were listed as "questionable" to play. Both are active.
On Saturday, the 49ers activated running back Elijah Mitchell from the injured reserve list. Additionally, the team elevated defensive lineman Michael Dwumfour and cornerback Janoris Jenkins from the practice squad, making them eligible to play against the Cardinals. All three are active.
Also active is wide receiver Deebo Samuel, who has not played since sustaining MCL and ankle sprains against the Tampa Bay Buccaneers on December 11, 2022.
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