With two touchdown passes and the victory over the Steelers, Purdy became the first quarterback in NFL history to win each of his first six career regular-season starts and throw at least two touchdown passes in each start.
Purdy also became the first quarterback in NFL history with a passer rating of 95 or higher in each of his first six career regular-season starts.
Brock Purdy's six regular-season starts:
| Week | Opponent | Result | Pass Yds | Pass TDs | Rating |
| Week 14, 2022 | vs. Tampa Bay | W 35-7 | 185 | 2 | 134.0 |
| Week 15, 2022 | at Seattle | W 21-13 | 217 | 2 | 117.0 |
| Week 16, 2022 | vs. Washington | W 37-20 | 234 | 2 | 114.6 |
| Week 17, 2022 | at Las Vegas | W 37-34 (OT) | 284 | 2 | 95.4 |
| Week 18, 2022 | vs. Arizona | W 38-13 | 178 | 3 | 141.3 |
| Week 1, 2023 | at Pittsburgh | W 30-17 | 220 | 2 | 111.3 |
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