The New York Giants will be without Saquon Barkley when they face the San Francisco 49ers on Thursday night. According to ESPN's Adam Schefter, the running back suffered an ankle sprain and will miss three weeks.


The good news for Giants fans is that the injury isn't as bad as initially believed. Barkley leads the Giants with 114 rushing yards, a rushing touchdown, and a receiving touchdown through the first two weeks of action. He has accounted for 155 total offensive yards this season.

The next man up for the Giants will be a familiar face to 49ers fans. Matt Breida will likely fill in for Barkley at Levi's Stadium on Thursday night. Breida has just three carries for 14 yards this season, his second with New York.

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