Running back Elijah Mitchell has been ruled out against the Cowboys, which means Jordan Mason will likely serve as Christian McCaffrey's backup.
Offensive lineman Jon Feliciano, who has been in the concussion protocol this week, is listed as "questionable."
Wide receiver Jauan Jennings, who was inactive against the Arizona Cardinals, is cleared to play. As are wide receiver Deebo Samuel, linebacker Dre Greenlaw, and cornerback Charvarius Ward.
Below are the official injury reports for the 49ers and Cowboys, provided by the 49ers Communications staff. Also included are Friday's practice participation reports.
San Francisco 49ers
Out
RB Elijah Mitchell (knee)
Questionable
C Jon Feliciano (concussion)
Dallas Cowboys
Out
TE Peyton Hendershot (ankle)
Questionable
LB Damone Clark (shoulder)
San Francisco 49ers Friday Practice
Did Not Participate In Practice
RB Elijah Mitchell (knee)
Full Participation in Practice
C Jon Feliciano (concussion), LB Dre Greenlaw (ankle), WR Jauan Jennings (shin), WR Deebo Samuel (ribs, knee), CB Charvarius Ward (heel)
Dallas Cowboys Friday Practice
Did Not Participate In Practice
TE Peyton Hendershot (ankle)
Limited Participation in Practice
LB Damone Clark (shoulder)
Full Participation in Practice
RB Rico Dowdle (hip), T Chuma Edoga (knee), S Malik Hooker (shoulder), WR CeeDee Lamb (not injury related - resting player, knee), G Zack Martin (not injury related - resting player, thigh), LB Micah Parsons (knee), T Tyron Smith (not injury related - resting player, knee)
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