The San Francisco 49ers may have slipped in several power rankings this week due to Sunday's loss to the Cleveland Browns. However, oddsmakers maintain their confidence in the 5-1 team, still considering it the betting favorite to win Super Bowl 58.

This loss ended the 49ers' impressive 15-game regular-season winning streak. In the NFC, only three teams stand at 5-1, with San Francisco joined by the Philadelphia Eagles and the Detroit Lions.

The biggest question centers on the impact of potential offensive absences for the 49ers. Wide receiver Deebo Samuel sustained a shoulder injury in the first quarter of the 19-17 loss, while tackle Trent Williams suffered an ankle injury, which he played through. Both players are considered day-to-day.

However, the most significant concern arises from the status of star running back Christian McCaffrey, who is dealing with an oblique/rib injury. His status remains unclear.


The NFL world watches to see if the 49ers can overcome the potential losses as they look to rebound on the road against the Minnesota Vikings on Monday night.

Below are the current Super Bowl odds from FanDuel Sportsbook.



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