The stage is set for an epic clash at Levi's Stadium next Sunday as the San Francisco 49ers square off against the Detroit Lions, with the teams vying for the right to represent the NFC in Super Bowl 58. The 49ers are coming off a thrilling 24-21 victory over the Green Bay Packers, while the Lions earned a 31-23 win over the Tampa Bay Buccaneers.

According to BetMGM, the home-team 49ers opened as early seven-point favorites over the visiting Lions in the NFC Championship Game showdown. San Francisco is the top-seeded team in the conference, while Detroit entered the playoffs as the third seed.

This game marks the 49ers' third consecutive appearance in the NFC Championship Game and their fourth in the last five years. In contrast, the Lions are returning to the title game for the first time since 1991. The matchup showcases the second-ranked 49ers offense against the 19th-ranked Lions defense and the third-ranked Lions offense facing the eighth-ranked 49ers defense.

The only lingering injury-related question for San Francisco surrounds the health of wide receiver Deebo Samuel, who exited Saturday night's game with a shoulder injury and could not return. We'll likely learn more about the extent of his injury from head coach Kyle Shanahan on Monday.

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