Previous game
The 49ers are coming off a loss to the Los Angeles Rams at SoFi Stadium. The offense was led by QB Brock Purdy, who completed 22 of 30 pass attempts for 292 yards and three touchdowns, with a passer rating of 137.1. WR Jauan Jennings recorded 11 receptions for 175 yards and three touchdowns, all of which set new single-game career highs. RB Jordan Mason contributed 19 carries for 77 yards on the ground.
Defensively, the 49ers held the Rams to 98 rushing yards. CB Charvarius Ward led the defense with nine tackles and one pass defensed, while DL Maliek Collins, DL Javon Hargrave, and DL Sam Okuayinonu each recorded a sack on Rams QB Matthew Stafford, marking their first sacks of the season.
The 49ers Communications staff provided the above breakdown.
Below is everything you need to know to follow the upcoming game.
When does the game start?
Sunday, September 29 at 1:05 p.m. PT
Where is the game being played?
Levi's Stadium in Santa Clara, California
Who are the head coaches?
49ers: Kyle Shanahan
Patriots: Jerod Mayo
Betting Odds
As of September 25, the 49ers are favored by 10 points in this game, with an over/under set at 39.5 points.
What channel is the game on?
Network: FOX
Play-by-Play: Joe Davis
Color Analyst: Greg Olsen
Sideline Reporter: Pam Oliver
Viewers outside the broadcast area can watch the game via NFL Sunday Ticket on YouTube TV or YouTube Premium, but a subscription to the package is required.
What areas will receive the broadcast?
The broadcast will be viewable within the markets designated below for those without NFL Sunday Ticket.
Where can I stream the game?
NFL Sunday Ticket subscribers can stream the game using the YouTube TV app. Those who purchased through YouTube Premium can watch via the YouTube app. Additionally, NFL+ subscribers can stream the game in its entirety once the matchup has been completed.
Bay Area fans can stream the game through the official 49ers app or at 49ers.com.
Where can I listen to the radio broadcast?
49ers Radio
Bay Area fans can listen on KGO 810 AM and The Bone 107.7 FM, where Greg Papa and Tim Ryan will call the game.
Jesu?s Za?rate and Carlos Yustis will call the game in Spanish. That broadcast can be heard at 49ers.com/news/Espanol.
Patriots Radio
New England area fans can listen on 98.5 The Sports Hub, where Bob Socci and Scott Zolak will call the game.
National Radio
Fans can listen to the game via ESPN Radio, where Mark Kestecher and Kelly Stouffer will call the game.
Streaming
NFL+ subscribers can listen to the game through that service.
Game discussion
Fans can discuss the game within our Niner Talk forum.
How has this series played out historically?
Matchups: 14
Series Record: 49ers lead series 9-5
49ers Home Record vs. Patriots: 49ers lead series 4-2
49ers Away Record vs. Patriots: 49ers lead series 5-3
First Meeting: 10/31/71, 49ers win 27-10, at SF
Last Meeting: 10/25/20, 49ers win 33-6, at NE
Current Streak: Won 1
Longest 49ers Win Streak: 6 (11/30/80 – 9/17/95)
Longest Patriots Win Streak: 3 (12/20/98 – 10/5/08)
Most 49ers Points: 41 (12/16/12): 49ers win 41-34, at NE
Most Patriots Points: 34 (12/16/12): 49ers win 41-34, at NE
49ers Shutouts: None
Patriots Shutouts: None
49ers Notes
- QB Brock Purdy had 333 yards (292 passing, 41 rushing) and 3 touchdown passes with 0 interceptions for a 137.1 rating in Week 3. It marked his 7th career game with 3+ touchdown passes. Purdy has 9 career games with a 130+ passer rating, the most by any quarterback in their first three NFL seasons. He has posted a 110+ rating in 15 of his first 24 career starts, making him one of only two quarterbacks (alongside Patrick Mahomes) with 15+ such games in their first 25 career starts.
- RB Jordan Mason recorded 88 scrimmage yards (77 rushing, 11 receiving) in Week 3. He ranks 2nd in the NFL with 324 rushing yards and is one of three players (Saquon Barkley and Alvin Kamara) with 75+ rushing yards in each of the first three weeks.
- WR Jauan Jennings set career highs in receptions (11), receiving yards (175), and receiving touchdowns (3) in Week 3. He became the second player in franchise history (joining Hall of Famer Jerry Rice) to record 10+ catches, 150+ receiving yards, and 3+ receiving touchdowns in a single game.
- WR Brandon Aiyuk had season highs in receptions (5) and receiving yards (48) in Week 3. He recorded 6 catches for 115 yards in the last meeting. Aiyuk has 5+ catches and 100+ receiving yards in 4 of his past 6 home games.
- TE George Kittle has posted 65+ receiving yards in 5 of his past 6 home games. He had 5 catches for 55 yards in the last meeting.
- LB Fred Warner recorded his 49th career pass deflection last week, the most among linebackers since entering the NFL in 2018. He also had 7 tackles and an interception in the last meeting.
- DL Nick Bosa registered a tackle for loss in Week 3, marking his 75th career TFL. He aims for his 3rd consecutive game with a TFL.
- DL Maliek Collins recorded his first sack of the season last week.
- CB Charvarius Ward led the team with 9 tackles in Week 3 and aims for his 4th consecutive game with a pass deflection.
- CB Deommodore Lenoir recorded his 9th career tackle for loss last week.
- S Ji'Ayir Brown had 2 pass deflections last week, marking his 2nd career game with 2+ PDs.
- S Talanoa Hufanga recorded 7 tackles in his season debut in Week 3.
Patriots Notes
- QB Jacoby Brissett completed 12 of 18 passes (66.7%) with 0 interceptions last week, marking his third consecutive start without an interception. He completed 22 of 34 passes (64.7%) for 314 yards and had a rushing touchdown in his only career start against San Francisco (10/8/17 with Indianapolis).
- QB Drake Maye (rookie) made his NFL debut in Week 3, completing 4 of 8 passes.
- RB Rhamondre Stevenson has 90+ scrimmage yards and a rushing touchdown in 2 of 3 games this season. He has 50+ scrimmage yards in 4 of his past 5 road games. He aims for his fourth consecutive game against an NFC team with 90+ scrimmage yards and a rushing touchdown.
- RB Antonio Gibson led the team with 29 rushing yards last week.
- TE Hunter Henry has 179 receiving yards (89.5 per game) in 2 career games against NFC West opponents.
- WR Demario Douglas had 7 catches for a team-high 69 yards in Week 3.
- DE Keion White aims for his third straight game with 6+ tackles. He has recorded 1.5+ sacks in 2 of 3 games this season and is tied for third in the NFL with 4 sacks in 2024. He also aims for his third consecutive game against an NFC opponent with a sack.
- DE Deatrich Wise Jr. recorded his first sack of the season last week. He has a sack in 2 of his last 3 road games.
- LB Joshua Uche had his first sack of the season in Week 3. He has a tackle for loss (TFL) in 3 of his past 4 road games.
- LB Anfernee Jennings had 6 tackles and 2 TFLs last week. He aims for his third consecutive game with 6+ tackles. He also had 5 tackles in the last meeting.
- LB Raekwon McMillan led the team with 10 tackles in Week 3, marking his third career game with 10+ tackles. He aims for his third consecutive game with 6+ tackles.
- LB Jahlani Tavai recorded 9 tackles and a TFL last week.
- CB Jonathan Jones had 7 tackles, a pass deflection (PD), and a forced fumble (FF) in Week 3, his eighth career FF. He aims for his fifth consecutive road game with a PD. Jones also recorded 7 tackles in the last meeting.
- S Kyle Dugger has 5+ tackles in 8 of his past 9 games. He has recorded a forced fumble and a PD in 2 of his past 3 road games.
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