49ers vs. Rams in Week 15: How to watch, stream, and listen, plus odds

The San Francisco 49ers return home to Levi's Stadium for the second consecutive week to face the Los Angeles Rams on Amazon Prime Video's Thursday Night Football. This matchup marks the 152nd all-time meeting between the two teams. The 49ers lead the series 78-70-3 and aim to improve to 39-35-2 at home against the Rams.

Previous game

The 49ers are coming off a dominant 38-13 victory over the Chicago Bears. On offense, the Niners were led by QB Brock Purdy, who posted a passer rating of 145.4 by completing 20 of 25 passing attempts for a season-high 325 yards and two touchdowns. WR Jauan Jennings hauled in seven receptions for 90 yards and two touchdowns. TE George Kittle caught all six of his targets for a team-high 151 yards. RB Isaac Guerendo contributed 15 carries for 78 yards and two rushing touchdowns while also adding two receptions for 50 yards. RB Patrick Taylor Jr. chipped in with seven carries for 25 yards and one rushing touchdown.

Defensively, San Francisco limited Chicago to just 68 rushing yards and recorded 7.0 sacks on Bears QB Caleb Williams. The defense was led by DL Yetur Gross-Matos, who tallied four tackles and a career-high 3.0 sacks. DL Leonard Floyd added two tackles and 2.0 sacks, while DL Maliek Collins contributed 1.0 sack on Williams.

Below is everything you need to know to follow the upcoming game.

When does the game start?

Thursday, December 12 at 5:15 p.m. PT

Where is the game being played?

Levi's Stadium in Santa Clara, California

Who are the head coaches?

49ers: Kyle Shanahan
Rams: Sean McVay

Betting Odds

As of December 10, the 49ers are favored by 2.5 points in this game, with an over/under set at 48.5 points.

What channel is the game on?

Network: Amazon Prime Video
Play-by-Play: Al Michaels
Color Analyst: Kirk Herbstreit
Sideline Reporter: Kaylee Hartung

What areas will receive the broadcast?

The game is available to anyone with access to Amazon Prime Video online streaming.

Bay Area fans can watch the broadcast on KTVU FOX 2. Los Angeles area fans can watch on KTTV FOX 11.

Where can I listen to the radio broadcast?

49ers Radio
Bay Area fans can listen on KGO 810 AM and The Bone 107.7 FM, where Greg Papa and Tim Ryan will call the game.

Jesu?s Za?rate and Carlos Yustis will call the game in Spanish. That broadcast can be heard at 49ers.com/news/Espanol.

Rams Radio
Los Angeles area fans can listen on ESPN 710 AM, where J.B. Long and Maurice Jones-Drew will call the game.

National Radio
Fans can listen via Westwood One Sports, where Ryan Radtke and Ron Rivera will call the game.

Streaming
NFL+ subscribers can listen to the game through that service.

Game discussion

Fans can discuss the game within our Niner Talk forum.

How has this series played out historically?

Matchups: 151
Series Record: 49ers lead series 78-70-3
49ers Home Record vs. Rams: 49ers lead series 38-35-2
49ers Away Record vs. Rams: 49ers lead series 40-35-1
First Meeting: 10/1/50, Rams win 35-14, at SF
Last Meeting: 9/22/24, Rams win 27-24, at LA
Current Streak: Lost 2
Longest 49ers Win Streak: 17 (12/17/90 – 12/27/98)
Longest Rams Win Streak: 10 (11/29/70 – 9/28/75)
Most 49ers Points: 48 (12/27/87): 49ers win 48-0, at SF
Most Rams Points: 56 (11/9/58): Rams win 56-7, at LA
49ers Shutouts: 9 (Last 9/12/16), 49ers win 28-0, at SF
Rams Shutouts: None

49ers Notes

QB BROCK PURDY: Completed 20 of 25 passes (80%) for 325 yards and 2 TDs with 0 INTs, achieving a season-high 145.4 passer rating in Week 14. Holds NFL records for most games (6) with a 140+ rating and most games (13) with a 120+ rating in the first three seasons of a career. Has 8 TDs vs. 1 INT for a 110.6 passer rating in 4 career Thursday starts, including 2+ TD passes and a 100+ rating in 3 of those 4 games. Threw for 292 yards and 3 TDs with 0 INTs for a 137.1 rating in the Week 3 meeting.
RB ISAAC GUERENDO (Rookie): Recorded a career-high 128 scrimmage yards (78 rushing, career-high 50 receiving) and had his first career game with 2 rushing TDs last week. Aims for his 3rd consecutive game with a rushing TD.
RB PATRICK TAYLOR: Scored his first rushing TD of the season last week.
TE GEORGE KITTLE: Posted 6 catches for 151 yards in Week 14, becoming the 3rd TE in NFL history (joining Travis Kelce and Hall of Famer Shannon Sharpe) with five games of 150+ receiving yards. Reached 7,000 receiving yards in 109 career games, the 3rd-fastest TE to hit that milestone. Leads all TEs in 2024 with 8 receiving TDs and ranks 3rd with 800 receiving yards. Has a TD catch in 4 of his last 5 home games against the Rams.
WR DEEBO SAMUEL: Tallied 533 scrimmage yards (133.3 per game) and 3 TDs (2 receiving, 1 rushing) in his last 4 Thursday games. Has 100+ scrimmage yards in 5 of his past 6 matchups against the Rams and 7 TDs (4 rushing, 3 receiving) in his last 8 meetings with the team.
WR JAUAN JENNINGS: Recorded 7 catches for 90 yards and 2 TDs last week, marking his 2nd career game with 2+ receiving TDs. Set career highs in catches (57), receiving yards (774), and receiving TDs (6) in 2024. Exploded for 11 catches, 175 yards, and 3 TDs in the Week 3 game against the Rams, setting single-game career highs.
LB FRED WARNER: Needs 9 tackles to reach 100 for the 7th consecutive season.
DL NICK BOSA: Recorded 5 sacks and 8 tackles for loss (TFL) in his last 7 games against the Rams.
DL LEONARD FLOYD: Has 1.5+ sacks in 3 of his last 4 games and recorded a sack in 4 of his past 5 home games. Previously tallied 33 sacks in 56 games with the Rams (2020-2022), including playoffs.
DL YETUR GROSS-MATOS: Logged a career-high 3 sacks last week and has 5 TFL in his last 4 games.
CB CHARVARIUS WARD: Aims for his 5th consecutive Thursday game with 2+ passes defensed (PD).

Rams Notes

QB MATTHEW STAFFORD: Passed for a season-high 320 yards and 2 TDs with 0 INTs, achieving a 132.6 passer rating last week. It marked his 64th career game with 300+ passing yards. Aims for his 5th consecutive game with 2+ TD passes and a 100+ passer rating. Posted a 105.6 rating in the Week 3 meeting against the 49ers. Ranks 5th in the NFL with 3,303 passing yards in 2024, recording his 12th career 3,000-yard season. Aims for his 3rd consecutive Thursday Night Football (TNF) game with 2+ TD passes and a 120+ passer rating.
RB KYREN WILLIAMS: Tallied 97 scrimmage yards (87 rushing, 10 receiving) and 2 rushing TDs last week. Became the 5th player since 2000 to record 1,000+ rushing yards and 12+ rushing TDs in 2 of his first 3 seasons. Aims for his 4th straight game with a rushing TD. Has 216 scrimmage yards (108 per game) and 5 TDs (3 rushing, 2 receiving) in 2 career games against San Francisco, including 100+ scrimmage yards and 2+ TDs in each matchup. Aims for his 3rd consecutive TNF game with 100+ scrimmage yards and a TD.
WR COOPER KUPP: Recorded 5 catches for 92 yards and his 6th receiving TD of the season last week. Has 4 receiving TDs in his past 4 games overall and 6 TDs in his last 7 Thursday appearances. Aims for his 3rd consecutive game in San Francisco with 11+ catches and 120+ receiving yards.
WR PUKA NACUA: Delivered 12 catches, 178 scrimmage yards (162 receiving, 16 rushing), and 2 TDs (1 receiving, 1 rushing) last week. Has 11 games with 100+ receiving yards, the 2nd most by a player in their first 2 seasons during the Super Bowl era. Recorded a TD catch in the last road game against San Francisco. Aims for his 3rd consecutive game with a TD reception.
LB BYRON YOUNG: Logged 2 tackles for loss (TFL), a sack, a pass deflection (PD), and a forced fumble (FF) in the Week 3 meeting. Aims for his 4th straight game against San Francisco with a sack.
DE KOBIE TURNER: Aims for his 3rd consecutive road game with a pass deflection (PD).
LB JARED VERSE: Leads all rookies with 11 tackles for loss (TFL) and ranks 3rd among rookies with 4.5 sacks.
DE BRADEN FISKE: Leads all rookies with 6 sacks and ranks 2nd with 8 tackles for loss (TFL).
LB CHRISTIAN ROZEBOOM: Aims for his 5th consecutive road game with 11+ tackles. Has a career-high 109 tackles in 2024.

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