49ers vs. Cardinals in Week 18: How to watch, stream, and listen, plus odds

The San Francisco 49ers will hit the road for their final game of the 2024 season, taking on the Arizona Cardinals at State Farm Stadium. This matchup marks the 67th all-time meeting between the two teams, with San Francisco aiming to improve their road record to 17-15 against the Cardinals.

Previous game

The 49ers are coming off a home loss to the Detroit Lions. Offensively, quarterback Brock Purdy led the charge, completing 27 of 35 pass attempts for 377 yards, three touchdowns, and two interceptions, earning a passer rating of 116.0. He also added three carries for 16 yards and a rushing touchdown. Wide receiver Ricky Pearsall recorded a career-high eight receptions for 141 yards and a touchdown, while tight end George Kittle caught all eight of his targets for 112 yards. Fullback Kyle Juszczyk, wide receiver Deebo Samuel Sr., and quarterback Joshua Dobbs each contributed a touchdown during the game.

On defense, the unit was anchored by defensive lineman Nick Bosa, who recorded a season-high eight tackles and 2.0 sacks on Lions quarterback Jared Goff. Defensive back Deommodore Lenoir added a team-high nine tackles to cap off a strong defensive effort.

Below is everything you need to know to follow the upcoming game.

When does the game start?

Sunday, January 5 at 1:25 p.m. PT

Where is the game being played?

State Farm Stadium in Glendale, Arizona

Who are the head coaches?

49ers: Kyle Shanahan
Cardinals: Jonathan Gannon

Betting Odds

As of January 1, the Cardinals are favored by four points in this game, with an over/under set at 42.5 points.

What channel is the game on?

Network: FOX
Play-By-Play: Chris Meyers
Color Analyst: Mark Schlereth
Sideline Reporter: Jen Hale

Viewers outside the broadcast area can watch the game via NFL Sunday Ticket on YouTube TV or YouTube Premium, but a subscription to the package is required.

What areas will receive the broadcast?

The broadcast will be viewable within the markets designated below for those without NFL Sunday Ticket.

Coverage map courtesy of 506sports.com

Where can I stream the game?

NFL Sunday Ticket subscribers can stream the game using the YouTube TV app. Those who purchased through YouTube Premium can watch via the YouTube app. Additionally, NFL+ subscribers can stream the game in its entirety once the matchup has been completed.

Bay Area fans can stream the game through the official 49ers app or at 49ers.com.

Where can I listen to the radio broadcast?

49ers Radio
Bay Area fans can listen on KGO 810 AM and The Bone 107.7 FM, where Greg Papa and Tim Ryan will call the game.

Jesu?s Za?rate and Carlos Yustis will call the game in Spanish. That broadcast can be heard at 49ers.com/news/Espanol.

Cardinals Radio
Arizona area fans can listen on Arizona Sports 98.7 FM, where Dave Pasch and Ron Wolfley will call the game.

Streaming
NFL+ subscribers can listen to the game through that service.

Game discussion

Fans can discuss the game within our Niner Talk forum.

How has this series played out historically?

Matchups: 66
Series Record: 49ers lead series 36-30
49ers Home Record vs. Cardinals: 49ers lead series 20-15
49ers Away Record vs. Cardinals: 49ers lead series 16-15
First Meeting: 11/18/51, Cardinals win 27-21, at SF*
Last Meeting: 10/6/24, Cardinals win 24-23, at SF
Current Streak: Lost 1
Longest 49ers Win Streak: 5 – 3 times (Last 9/13/09 – 11/20/11)
Longest Cardinals Win Streak: 8 – (9/27/15 – 10/28/18)
Most 49ers Points: 56 (10/18/92): 49ers win 56-17, at SF
Most Cardinals Points: 34 – 2 times, (Last 9/10/06): Cardinals win 34-27, at Arz.
49ers Shutouts: None
Cardinals Shutouts: None
*Chicago Cardinals

49ers Notes

QB Brock Purdy passed for a career-high 377 yards and accounted for 4 total touchdowns (3 passing, 1 rushing) with 2 interceptions, earning a 116 passer rating in Week 17. He now has 15 career games with 2+ touchdown passes and a 115+ passer rating, the most by a quarterback in their first three NFL seasons.
QB Josh Dobbs scored a rushing touchdown in his season debut last week. In 2023, he passed for 1,569 yards and 8 touchdowns while rushing for 258 yards and 3 scores in 8 starts with Arizona.
QB Brandon Allen threw for 199 yards and a touchdown in his lone start of the season (Week 12 at Green Bay).
RB Isaac Guerendo (rookie) totaled 99 scrimmage yards last week, including a career-high 65 receiving yards and 34 rushing yards. He aims for his fourth consecutive game with 75+ scrimmage yards.
FB Kyle Juszczyk recorded his first receiving touchdown of the season last week, the 17th of his career.
TE George Kittle had 8 receptions for 112 yards last week, marking his 21st career game with 100+ receiving yards, the fourth-most by a tight end in their first eight seasons. In 2024, he ranks second among tight ends in receiving touchdowns (8), third in receiving yards (1,079), and fifth in receptions (76). He became the fifth tight end in NFL history with four or more career seasons of 1,000+ receiving yards. Kittle aims for his third straight game with 100+ receiving yards. In the Week 5 matchup, he had 8 catches for 64 yards and a touchdown and has 6 receiving touchdowns in his past 6 games against Arizona.
WR Deebo Samuel recorded his third receiving touchdown of the season last week and aims for his third consecutive game with a touchdown catch. He had 2 receiving touchdowns in his last road game against Arizona and seeks his fourth straight game at Arizona with a touchdown catch.
WR Jauan Jennings tallied 7 receptions for 67 yards last week. He needs 77 receiving yards to achieve his first career 1,000-yard season.
WR Ricky Pearsall set career highs last week with 8 receptions and 141 receiving yards, adding his second career receiving touchdown. His 141 yards are the third-most by a 49ers rookie in franchise history.
LB Fred Warner is one of two players (alongside Bobby Wagner) to record 115+ tackles in each of the past 7 seasons. He logged 12 tackles in the Week 5 matchup.
DL Nick Bosa tied his career highs in tackles (8) and tackles for loss (4) and added 2 sacks last week. He has recorded 9+ sacks in 5 of his 6 career seasons and is one of two players (with Myles Garrett) to notch 15+ tackles for loss in each of the past 4 seasons.
CB Deommodore Lenoir led the team with a season-high 9 tackles last week.
CB Renardo Green (rookie) recorded his 10th pass deflection of the season last week and has at least one pass deflection in 7 of his past 8 games. He aims for his sixth straight road game with 5+ tackles and a pass deflection.

Cardinals Notes

QB Kyler Murray passed for 321 yards last week, marking his 15th career 300-yard game. He has 3,609 passing yards in 2024, his fourth career season with 3,500+ passing yards (2019-21). At home this season, Murray has totaled 12 touchdowns (9 passing, 3 rushing) with a 99 passer rating in 8 starts. In the Week 5 matchup, he recorded 278 total yards (195 passing, 83 rushing) and 2 touchdowns (1 passing, 1 rushing).
RB James Conner has set career highs in scrimmage yards (1,508) and rushing yards (1,094) in 2024. He aims for his fourth consecutive home game with a touchdown and his seventh in a row at home with 100+ scrimmage yards. In the Week 5 matchup, he posted 100 scrimmage yards (86 rushing, 14 receiving) and has 6 touchdowns (5 rushing, 1 receiving) in his past 6 games against San Francisco.
RB Michael Carter tallied a career-high 70 rushing yards last week.
TE Trey McBride recorded 12 receptions for 123 yards and his first receiving touchdown of the season last week, his fifth career touchdown catch. He is the first tight end in NFL history with three games of 12+ receptions in a single season. McBride ranks second among tight ends with a career-high 104 receptions, the ninth-most ever by a tight end in a single season. He had 10 catches for 102 yards in his last home game against San Francisco.
WR Marvin Harrison Jr. (rookie) had 6 receptions for 96 yards last week and is tied for second among rookies with 7 receiving touchdowns.
S Budda Baker recorded 7 tackles and 2 passes defensed last week. He ranks second in the NFL with a career-high 155 tackles in 2024, the most by a defensive back in a single season since 2000. Baker aims for his 12th consecutive game against San Francisco with 5+ tackles.
LB Kyzir White led the team with 8 tackles last week and has 127 tackles this season, marking his third career 100-tackle season. He recorded an interception in the Week 5 matchup.
LB Mack Wilson has recorded 5+ tackles in 3 of his past 4 games. He had a fumble recovery and an interception in the Week 5 meeting.
S Jalen Thompson aims for his fifth consecutive game with 6+ tackles. He also tallied 2 passes defensed in the Week 5 matchup.

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