A hip injury to running back Frank Gore opened the door for Brian Westbrook's 136 yard, one touchdown performance.
Quarterback Troy Smith was 11 of 23 for 129 yards, one touchdown and an interception.
On Sunday, the 49ers will face a tough test in Green Bay as they take on the Packers at Lambeau Field.
Elsewhere in the division, the Seahawks will face the Panthers at in Seattle and the Cardinals and Rams will battle each other in Arizona.
View gameday stats at NFL.com's Game Center.
You can also discuss the game with fans in the 49erswebzone.com forums.
More San Francisco 49ers News
-
Kyle Shanahan handed over 49ers' play-calling duties against Cardinals
The San Francisco 49ers offense racked up 436 total yards on Sunday against the Arizona Cardinals at State Farm Stadium despite falling 47-24 in their season finale. It marked the team's fifth-highest yardage total this season. Their 298 passing yards were the fourth-most in... -
Only one 49ers player makes Next Gen Stats 2024 All-Pro Team
Tight end George Kittle was the only San Francisco 49ers player named to the Next Gen Stats 2024 All-Pro Team, following the inclusion of Kittle, Christian McCaffrey, Brandon Aiyuk, and Fred Warner in 2023. After a disappointing 6-11 season that saw the 49ers miss the playoffs... -
Sidelined 49ers: Who's out against the Cardinals?
The San Francisco 49ers aim to end their injury-plagued season on a high note with a Week 18 matchup against the Arizona Cardinals at State Farm Stadium. However, several key players will be unavailable as the team wraps up a disappointing campaign. RELATED: 49ers announce... -
How PFF graded Kyle Juszczyk, Nick Bosa, other 49ers players vs. Cardinals, plus snap counts
The San Francisco 49ers concluded their season with a 6-11 record following a 47-24 loss to the Arizona Cardinals in Week 18. Pro Football Focus has released its grades and snap counts from the game, shedding light on which 49ers players excelled and which struggled. Below are...