Iupati was a first round selection out of Idaho in the 2010 NFL Draft.
The 49ers have already had injuries to Vernon Davis and Eric Reid in this game against the Panthers.
More San Francisco 49ers News
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Bears' head coach decision could impact 49ers' defensive coordinator hunt
ESPN's Adam Schefter reported that the Chicago Bears have chosen former Detroit Lions offensive coordinator Ben Johnson as their next head coach and are finalizing contract details. The Bears land one of the most intriguing names on the market, a move that could impact the San... -
49ers bolster defensive front in latest CBS Sports mock draft
Josh Edwards of CBS Sports unveiled his latest mock draft on Thursday, projecting the San Francisco 49ers to bolster their defensive front with the 11th overall pick. Following a disappointing 6-11 season, Edwards predicts that general manager John Lynch and his team will... -
49ers legend Patrick Willis names favorite current linebackers
Hall of Fame linebacker Patrick Willis recently spoke with Touchdown Wire's Ed Easton Jr., offering his insights on today's NFL game. Willis, who spent his entire eight-year career with the San Francisco 49ers, earned five first-team All-Pro honors and was selected to the Pro... -
Another option emerges for 49ers' DC candidate Robert Saleh
Former New York Jets head coach Robert Saleh is gaining attention in the coaching market. He is scheduled to interview with the Las Vegas Raiders tomorrow for their head coach vacancy, having already met with the Jacksonville Jaguars for the same role. Additionally, Saleh...