According to Matt Barrows of the Sacramento Bee, the 49ers' medical staff determined that Hyde would benefit from not playing against the Rams. Reggie Bush or Mike Davis will start Sunday.
WR Anquan Boldin is listed as questionable with a hamstring injury. However, when asked if he'd play on Sunday morning, he said, "Oh, there ain't no doubt in my mind." Boldin missed practice on Friday.
The 49ers kick off against the Rams on Sunday at 10 AM.
Below are the injury reports for both teams that were released on Friday.
San Francisco 49ers
Out: RB Carlos Hyde (foot)
Questionable: WR Anquan Boldin (hamstring)
Probable: G Alex Boone (shoulder, knee), LB Navorro Bowman (shoulder), LB Ahmad Brooks (shoulder), DT Tony Jerod-Eddie (not injury related), QB Colin Kaepernick (right hand), T Erik Pears (back), S Eric Reid (chest), T Joe Staley (shoulder)
St. Louis Rams
Out: DE Chris Long (knee)
Questionable: DE William Hayes (thigh), RB Tre Mason (ankle), S T.J. McDonald (shoulder), DE Robert Quinn (knee)
Probable: DT Nick Fairley (illness), TE Lance Kendricks (thumb), LB James Laurinaitis (elbow)
Related News
More San Francisco 49ers News
-
49ers vs. Cardinals injury updates: Guerendo, Mustapha, Hufanga ruled out
The San Francisco 49ers entered Sunday's season finale against the Arizona Cardinals with a depleted roster. Quarterback Josh Dobbs took the reins in place of Brock Purdy, who is sidelined with a right elbow contusion and nerve inflammation sustained during last week's matchup... -
Sidelined 49ers: Who's out against the Cardinals?
The San Francisco 49ers aim to end their injury-plagued season on a high note with a Week 18 matchup against the Arizona Cardinals at State Farm Stadium. However, several key players will be unavailable as the team wraps up a disappointing campaign. RELATED: 49ers announce... -
Kyle Shanahan handed over 49ers' play-calling duties against Cardinals
The San Francisco 49ers offense racked up 436 total yards on Sunday against the Arizona Cardinals at State Farm Stadium despite falling 47-24 in their season finale. It marked the team's fifth-highest yardage total this season. Their 298 passing yards were the fourth-most in... -
Will Brock Purdy hold out if negotiations stall? The 49ers QB weighs in
San Francisco 49ers quarterback Brock Purdy recently expressed his desire to finalize a contract extension quickly to avoid offseason distractions. However, all of that is in the hands of his agent and the 49ers, with previous standoffs a reminder of how these talks can stretch...