Christian McCaffrey downgraded to out with knee injury

49ers running back Christian McCaffrey will not return to Sunday's matchup against the Bills. McCaffrey has been downgraded to out with the knee injury he.....

San Francisco 49ers

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SUN

5

jan

Sun, Jan 5 | 9:25 PM · State Farm Stadium, One Cardinals Drive, Glendale, AZ

49ers at Cardinals

✔ Arizona Cardinals - San Francisco 49ers

TUE

31

dec

Tue, Dec 31 | 1:15 AM · Levi's Stadium, 4900 Marie P DeBartolo Way, Santa Clara, CA

Lions at 49ers

✔ San Francisco 49ers - Detroit Lions

SUN

22

dec

Sun, Dec 22 | 9:25 PM · Hard Rock Stadium, 2269 Northwest 199th Street, Miami Gardens, FL

49ers at Dolphins

✔ Miami Dolphins - San Francisco 49ers

FRI

13

dec

Fri, Dec 13 | 1:15 AM · Levi's Stadium, 4900 Marie P DeBartolo Way, Santa Clara, CA

Rams at 49ers

✔ San Francisco 49ers - Los Angeles Rams

SUN

8

dec

Sun, Dec 8 | 9:25 PM · Levi's Stadium, 4900 Marie P DeBartolo Way, Santa Clara, CA

Bears at 49ers

✔ San Francisco 49ers - Chicago Bears

MON

2

dec

Mon, Dec 2 | 1:20 AM · Highmark Stadium, One Bills Drive, Orchard Park, NY

49ers at Bills

✔ Buffalo Bills - San Francisco 49ers

SUN

24

nov

Sun, Nov 24 | 9:25 PM · Lambeau Field, 1265 Lombardi Avenue, Green Bay, WI

49ers at Packers

✔ Green Bay Packers - San Francisco 49ers

SUN

17

nov

Sun, Nov 17 | 9:05 PM · Levi's Stadium, 4900 Marie P DeBartolo Way, Santa Clara, CA

Seahawks at 49ers

✔ San Francisco 49ers - Seattle Seahawks

SUN

10

nov

Sun, Nov 10 | 6:00 PM · Raymond James Stadium, 4201 North Dale Mabry Highway, Tampa, FL

49ers at Buccaneers

✔ Tampa Bay Buccaneers - San Francisco 49ers

MON

28

oct

Mon, Oct 28 | 12:20 AM · Levi's Stadium, 4900 Marie P DeBartolo Way, Santa Clara, CA

Cowboys at 49ers

✔ San Francisco 49ers - Dallas Cowboys

SUN

20

oct

Sun, Oct 20 | 8:25 PM · Levi's Stadium, 4900 Marie P DeBartolo Way, Santa Clara, CA

Chiefs at 49ers

✔ San Francisco 49ers - Kansas City Chiefs

FRI

11

oct

Fri, Oct 11 | 12:15 AM · Lumen Field, 800 Occidental Avenue South, Seattle, WA

49ers at Seahawks

✔ Seattle Seahawks - San Francisco 49ers

SUN

6

oct

Sun, Oct 6 | 8:05 PM · Levi's Stadium, 4900 Marie P DeBartolo Way, Santa Clara, CA

Cardinals at 49ers

✔ San Francisco 49ers - Arizona Cardinals