Shanahan informed reporters earlier this week Breida would be out a couple of weeks with an ankle injury, while Staley's broken finger suffered against the Seattle Seahawks a week ago would keep him out roughly the same length.
Gould's absence opens up the door for rookie kicker Chase McLaughlin to gain some redemption after his overtime miss versus Seattle a week ago.
Al-Shaair (concussion) and Jones (groin) could return in a week or two.
Yet Kittle's absence figures to have a notable effect on San Francisco's offense. On the plus side, wide receiver Emmanuel Sanders is expected to play despite suffering a ribs injury in Week 10. The Niners offense, which was without Kittle a week ago, struggled once Sanders exited the game.
Sanders' presence will be something to watch versus Arizona, and the 49ers and Cardinals will kick off at 4:05 p.m. ET from Levi's Stadium.
Peter Panacy has been writing about the 49ers since 2011 for outlets like Bleacher Report, Niner Noise, 49ers Webzone, and is occasionally heard as a guest on San Francisco's 95.7 FM The Game and the Niners' flagship station, KNBR 680. Feel free to follow him, or direct any inquiries to his Twitter account.
49ers vs. Cardinals in Week 18: How to watch, stream, and listen, plus odds
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The San Francisco 49ers will hit the road for their final game of the 2024 season, taking on the Arizona Cardinals at State Farm Stadium. This matchup marks the 67th all-time meeting between the two teams, with San Francisco aiming to improve their road record to 17-15 against...
Josh Dobbs, Nick Sorensen, Chris Foerster preview 49ers-Cardinals Week 18 matchup
By Site Staff
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San Francisco 49ers head coach Kyle Shanahan spoke to reporters ahead of Wednesday's practice as the team prepares for its Week 18 matchup against the Arizona Cardinals. Here's everything he said.
Transcript provided by the San Francisco 49ers Communications staff.
Opening...
49ers practice and media schedule: Preparing for the Week 18 matchup vs. Cardinals
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The San Francisco 49ers are set to hold three full practices this week as they gear up for their Week 18 matchup against the Arizona Cardinals, marking the final game of the season.
Head coach Kyle Shanahan, defensive coordinator Nick Sorensen, and offensive line/run game...
