49ers 2021 Schedule
- Preseason
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Kansas City ChiefsSaturday, August 14 at 5:30 PMKPIX5
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atLos Angeles ChargersSunday, August 22 at 4:30 PMKPIX5
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Las Vegas RaidersSunday, August 29 at 1:00 PMKPIX5
- Regular Season
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Week 1atDetroit LionsSunday, September 12 at 10:00 AMFOX
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Week 2atPhiladelphia EaglesSunday, September 19 at 10:00 AMFOX
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Week 3Green Bay PackersSunday, September 26 at 5:20 PMNBC
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Week 4Seattle SeahawksSunday, October 3 at 1:05 PMFOX
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Week 5atArizona CardinalsSunday, October 10 at 1:25 PMFOX
- BYE
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Week 7Indianapolis ColtsSunday, October 24 at 5:20 PMNBC
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Week 8atChicago BearsSunday, October 31 at 10:00 AMFOX
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Week 9Arizona CardinalsSunday, November 7 at 1:25 PMFOX
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Week 10Los Angeles RamsMonday, November 15 at 5:15 PMESPN
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Week 11atJacksonville JaguarsSunday, November 21 at 10:00 AMFOX
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Week 12Minnesota VikingsSunday, November 28 at 1:25 PMFOX
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Week 13atSeattle SeahawksSunday, December 5 at 5:20 PMNBC
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Week 14atCincinnati BengalsSunday, December 12 at 10:00 AMCBS
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Week 15Atlanta FalconsSunday, December 19 at 1:05 PMCBS
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Week 16atTennessee TitansThursday, December 23 at 5:20 PMNFLN
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Week 17Houston TexansSunday, January 2 at 1:05 PMCBS
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Week 18atLos Angeles RamsSunday, January 9 at 1:25 PMFOX
* All times Pacific