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Below are the official injury status reports for the two teams.
San Francisco 49ers
Out
WR Deebo Samuel (calf)
Doubtful
TE George Kittle (hamstring)
Questionable
DE Nick Bosa (rib), CB Charvarius Ward (hamstring, knee)
Los Angeles Rams
Out
TE Davis Allen (back), WR Cooper Kupp (ankle)
Questionable
DT Bobby Brown (ankle), CB Cobie Durant (toe), K Joshua Karty (groin)
Notes
Wide receiver Deebo Samuel is nursing a hamstring injury sustained at the end of the Week 2 loss to the Minnesota Vikings and is expected to miss a couple of games.
Cornerback Charvarius Ward sat out Thursday's practice due to knee and hamstring issues. Defensive coordinator Nick Sorensen explained that Ward was experiencing some soreness, and his absence was a precautionary measure.
Tight end George Kittle is also dealing with a hamstring injury and has missed the last two practices of the week. He has not progressed well and is doubtful for Week 3.
Defensive end Nick Bosa appeared on Thursday's injury report with a rib injury suffered during a one-on-one drill but has practiced every day since Wednesday in at least a limited capacity.
Safety Talanoa Hufanga has no game status designation, indicating he's set to make his season debut after recovering from an ACL injury suffered in November 2023.
Running back Christian McCaffrey remains on injured reserve, which made him ineligible for four games. He will miss two more matchups after Sunday's contest against the Rams, assuming he recovers from the Achilles tendinitis that has been troubling him.
Below are Friday's practice participation reports for both the 49ers and Rams, which were provided by the 49ers Communications staff.
San Francisco 49ers Friday Practice
Did Not Participate In Practice
TE George Kittle (hamstring), WR Deebo Samuel (calf)
Limited Participation in Practice
DE Nick Bosa (rib), CB Charvarius Ward (hamstring, knee)
Full Participation in Practice
S Talanoa Hufanga (knee), LB Dee Winters (ankle)
Los Angeles Rams Friday Practice
Did Not Participate In Practice
TE Davis Allen (back), WR Cooper Kupp (ankle), CB Tre'Davious White (not injury related-rest)
Limited Participation in Practice
DT Bobby Brown (ankle), CB Cobie Durant (toe), K Joshua Karty (groin)
G Kevin Dotson (foot)
