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Please post pregame and game time reactions here. Threads created during game time may be locked/merged.
- September 18, 2022; 1:05 pm (PT)
- 49ers -8.5; O/U 40.5
- Venue: Levi's Stadium
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Injury Report:
49ers
Out: OL Daniel Brunskill (hamstring)
Questionable: TE George Kittle (groin)
Seahawks
Doubtful: S Joey Blount (hamstring)
Questionable: CB Artie Burns (groin), CB Justin Coleman (calf)
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