SANTA CLARA — The 49ers' NFC matchup with the Chicago Bears on Sunday will be Isaac Guerendo's chance to shine. The rookie running back has had few chances to show what he is capable of in his debut NFL season, but with both Christian McCaffrey and Jordan Mason out for at least the next four games, Guerendo will get his shot. The Wisconsin product believes running backs coach Bobby Turner has prepared him well. "I've had the same mentality the whole time," Guerendo said Wednesday. "I always give credit to Coach T preparing everybody like they are going to be the starters. That way when moments do come up, I'm ready for it." Guerendo spent five years at Wisconsin before transferring to Louisville for his final college season, where he registered 132 carries for 810 yards and 11 touchdowns while also catching 22 passes for 234 yards. The 49ers selected the versatile ball carrier in the fourth round (No. 129) of the 2024 NFL Draft, and outside of college, Guerendo admittedly had not played running back since the fourth grade and instead spent the entirety of his pre-NCAA football career playing wide receiver. The 24-year-old has leaned on several veterans in the 49ers' locker room,...
How Guerendo has prepared for opportunity as 49ers’ lead back
The above videos are auto-populated by an affiliate.
Follow us on:
The above link leads to an external page. 49ers Webzone has no control over its contents.
Similar Article Found
Next man up: Isaac Guerendo ready to lead 49ers backfield
Next man up: Isaac Guerendo ready to lead 49ers backfield
By David Bonilla
Dec 5, 2024
San Francisco 49ers rookie Isaac Guerendo didn't transition to playing running back until he arrived at Wisconsin. Before that, he was a wide receiver but understood a position change was necessary at the collegiate level.
That carried throughout his college career, even after...
Read Next
"We've earned this": 49ers discuss No. 1 seed opportunity; latest injury updates
"We've earned this": 49ers discuss No. 1 seed opportunity; latest injury updates
By David Bonilla
Dec 28, 2025
The San Francisco 49ers held off the Chicago Bears 42-38 on Sunday night at Levi's Stadium, keeping their push for the NFC's No. 1 seed alive. The win sets up a high-stakes Week 18 matchup against the Seattle Seahawks in Santa Clara, where the NFC West title, the conference's...
Purdy vs. Seattle: A Major Prove-It Opportunity for the 49ers Quarterback
Purdy vs. Seattle: A Major Prove-It Opportunity for the 49ers Quarterback
By Jesse Dumas
Dec 31, 2025
Last Sunday night's mostly defense-optional showdown gave us a play that belongs in the Canton, Ohio vault of NFL highlights. Brock Purdy faked the handoff, rolled left, and suddenly had Austin Booker and the very spherical Andrew Billings chasing him like Labradors after...
49ers injury update: George Kittle has 'a chance' to play vs. Bears
49ers injury update: George Kittle has 'a chance' to play vs. Bears
By David Bonilla
Dec 24, 2025
San Francisco 49ers tight end George Kittle avoided a worst-case scenario after suffering an ankle injury Monday night against the Indianapolis Colts.
ESPN's Jeremy Fowler reported that Kittle sustained a mid-to-low ankle sprain rather than a high-ankle sprain, which...
49ers Notebook: Inside the frantic final play against the Bears; Former Bear Jake Tonges has a night to remember; What makes Kyle Shanahan a great playcaller?
49ers Notebook: Inside the frantic final play against the Bears; Former Bear Jake Tonges has a night to remember; What makes Kyle Shanahan a great playcaller?
By Kirk Larrabee
Dec 29, 2025
Sunday night's 42-38 win over the Chicago Bears was one to remember for the San Francisco 49ers, who now stand at 12-4 with one more win needed to secure home field advantage throughout the playoffs.
The game was a back-and-forth affair, with both offenses putting up big...
Latest
- Trent Williams, George Kittle, 3 other 49ers questionable to play vs. Seahawks
- 49ers mailbag: More two TE sets with Jake Tonges? Will Trent Williams play Saturday? What are the rules for signing players from teams not in postseason?
- Brock Purdy and Jauan Jennings find late-season groove ahead of playoff push
- Only one 49ers player named to Barnwell's 2025 NFL All-Pro team
- 49ers vs. Seahawks injury report: 2 players miss Wednesday's practice
Trending News
-
49ers Webzone • Dec 31, 2025
-
49ers Webzone • 21 hrs
-
49ers Webzone • 21 hrs
-
49ers Webzone • 3 hrs
-
49ers Webzone • Dec 31, 2025
-
49ers Webzone • 6 hrs