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49ers RB Isaac Guerendo to Miss Week 16 with a Hamstring Injury

17 hrs ago

The 49ers will have to start their fourth different running back this Sunday against the Miami Dolphins. That's because rookie running back Isaac Guerendo is likely to miss Sunday's game with a hamstring injury he suffered this past Thursday night.

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49ers injuries: Trent Williams may not return this season; Isaac Guerendo won't practice

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