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49ers vs. Cardinals injury report: Deebo out; Kittle questionable

Jan 3, 2025 at 3:40 PM

SANTA CLARA — The 49ers will be missing several of their stars heading into their season finale against the Arizona Cardinals. After missing practice all week, Deebo Samuel will miss the team's Week 18 game. The wideout injured his wrist and ribs in Monday night's loss to the Detroit Lions, and like Brock Purdy (elbow), will watch the game from the sidelines. San Francisco has both good and not-so-good news on the offensive line with Spencer Burford set to miss a second straight game with a calf injury. Colton MccKivitz, however, is listed as questionable with a knee injury and appears ready to play after missing two practices this week. Tight end George Kittle, who is listed as questionable for the finale, likely will be helping out the offensive line that will be anchored by linemen who have very little experience with the 49ers' system. Charlie Heck and Austen Pleasants likely will rotate at left tackle for a second straight game. On the defensive side of the ball, the 49ers will be missing both cornerback Deommodore Lenoir (shoulder) and defensive lineman Robert Beal (ankle) on Sunday. But they received good news regarding Nick Bosa, who is only listed as questionable and...

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